武警医学Issue(12)：1205-1208,1211,5.
间质性膀胱炎／膀胱疼痛综合征水扩张联合不同药物灌注疗效评估
Efficacy assessment of bladder hydrodistension combined with drug intravesical instilla-tion for treatment of interstitial cystitis/bladder pain syndrome
摘要
Abstract
Objective To explore the efficacy of bladder hydrodistension combined with drug intravesical therapy in treatment of IC/BPS.Methods O’ Leary-Sant questionnaire and PUF were used to assess the patients’ symptoms.Depending on the intravesi-cal drugs, the patients were divided into groups A and B.To group A, hyaluronic acid was administered intravesically; To group B, heparin cocktail was given intravesically.The efficacy was comparied between the two groups before and after treatment.Results Af-ter 6 months of treatment, the total effective rates were 88.6%(group A) and 86.1%(B group) respectively.Comparing the total ef-fective rates of the two groups, there was no statistically significant difference (P=0.074).Compared with before treatment, the ob-served indicators in the two groups of patients were improved(P<0.05) after treatment at 1,3,6 months.1 month after treatment, the difference between the two groups was not significant (P>0.05), 3 months and 6 months after treatment, differences between the two groups were statistically significant(P<0.05).Conclusions Hydrodistension combined with intravesical instillation of hyaluronic acid or heparin cocktail method can effectively alleviate the symptoms of patients with IC/BPS; hyaluronic acid is superior to heparin cocktail method in the long-term efficacy.关键词
间质性膀胱炎/膀胱疼痛综合征/水扩张/膀胱灌注Key words
interstitial cystitis/bladder pain syndrome/hydrodistension/intravesical instillation分类
临床医学引用本文复制引用
陈强,周述银,张茂,刘德云..间质性膀胱炎／膀胱疼痛综合征水扩张联合不同药物灌注疗效评估[J].武警医学,2014,(12):1205-1208,1211,5.
