武警医学Issue(12)：1245-1247,3.
维生素 D3对妊娠糖尿病炎性因子及胰岛素抵抗的影响
Research on the therapeutic effect of Vitamin D3 in gestational diabetes factor
摘要
Abstract
Objective To explore the effect of Vitamin D3 in gestational diabetes inflammation factor.Methods Sixty pa-tients with gestational diabetes were randomly divided into two groups:30 cases of control group ( treatment group) , 30 cases of obser-vation group ( foundation treatment group plus vitamin D3) .On the basis of the control group, treatment observation group was given o-ral vitamin D3 1000 U/d for 4 weeks.Before and after treatment, high-sensitivity c-reactive protein ( Hs-CRP) , tumor necrosis factor alpha and insulin resistance were compared between two groups.Results Before and after treatment ,observation group hs-CRP ( mg/L) was decreased obviously, respectively 6.18 ±2.99,3.80 ±1.60;control group was 5.78 ±2.24, 5.05 ±1.90.There was statisti-cally significant difference (P<0.05).Before and after treatment ,observation group TNF-α(pg/ml) was decreased obviously, re-spectively 36.33 ±5.45,27.45 ±5.01;control group was 40.25 ±19.25,35.35 ±14.50.There was statistically significant difference (P<0.05).After treatment, insulin resistance of observation group was improved (P<0.05).Conclusions High Vitamin D3 level in blood can improve glucose metabolism during pregnancy through increasing insulin sensitivity.关键词
妊娠糖尿病/高敏C反应蛋白/肿瘤坏死因子α/胰岛素抵抗Key words
gestational diabetes mellitus/hs-CRP/TNF-α/insulin resistance分类
医药卫生引用本文复制引用
侯雪晶,路春梅..维生素 D3对妊娠糖尿病炎性因子及胰岛素抵抗的影响[J].武警医学,2014,(12):1245-1247,3.基金项目
河北省秦皇岛市科技支撑计划项目 （）
