武警医学Issue(12)：1256-1258,3.
Ki67、EGFR在三阴性及非三阴性乳腺癌中的表达与相关性分析
Expression of Ki67,EGFR in triple negative breast cancer and correlation analysis
张淼 1任力 1胡蓉 1褚晓雨 1朱广卿1
作者信息
摘要
Abstract
Objective To study Ki67, EGFR in non-triple negative and triple negative expression in breast cancer, and to ex-plore the correlation between Ki67 and EGFR gene expression.Methods Immune histochemical method was used to detect Ki67 in specimens of 513 cases of breast cancer and the expression of EGFR, comparing both in triple negative and none triple negative breast cancer, and the correlation was analyzed by chi square and Spearman method.Results Ki67 positive expression rate in triple negative breast cancer tissues (94.32%) was significantly higher than that in triple negative breast cancer (80.47%) (P<0.05).Triple neg-ative rate of EGFR expression in breast cancer tissue (68.18%) was significantly higher than that of non-triple negative breast cancer (11.76%) (P<0.05).Conclusions Ki67 and EGFR expression in triple negative breast cancer increases,but no correlation be-tween both,has important significance in breast cancer prognosis judgement.关键词
三阴性乳腺癌/Ki67/表皮生长因子受体Key words
triple negative breast cancer/Ki67/EGFR分类
医药卫生引用本文复制引用
张淼,任力,胡蓉,褚晓雨,朱广卿..Ki67、EGFR在三阴性及非三阴性乳腺癌中的表达与相关性分析[J].武警医学,2014,(12):1256-1258,3.
