武警医学Issue(1)：56-59,4.
卒中后发生抑郁的相关因素探讨
Clinical evaluation of post-stroke depression-related factors
摘要
Abstract
Objective To evaluate the factors related to post-stroke depression ( PSD) .Methods 265 patients were divided into two groups .Control group included 175 patients without depression while PSD group included 90 patients with depression after stroke.Gender, age, education, past history of hypertension, diabetes, coronary heart disease, stroke and depression,scores of Scan-dinavian Stroke Scale ( SSS ) and activities of daily living ( ADL ) , serum level of homocysteine , lesion location were analyzed . Result Education in PSD group was(4.4 ±4.7)years and in control group was (5.7 ±4.7)years(P<0.05).Past depression inci-dence in PSD group was 15.6%and in control group was 5.1%(P<0.05).SSS score,ADL score and concentration of serum homo-cysteine in both groups were (23.7 ±5.8),(13.72 ±5.6),(24.67 ±6.24)μmol/L and (19.5 ±5.1),(26.35 ±10.2),(14.58 ± 5.21) μmol/L, respectively.Differences were all significant (P<0.05).Frontal lobe lesion rate in PSD group was 22.2% and in control group was 8.6%,there was also a significant difference (P<0.05).Logistic regression analysis indicated that scores of SSS and ADL and frontal lobel lesion had most important influence on PSD .Conclusions Education, scores of SSS and ADL , concentra-tion of serum homocysteine , past history of depression and frontal lobe lesion are correlated with PSD .PSD is a disease caused by a number of factors together .关键词
卒中/抑郁/多因素Key words
stroke/depression/multi-factor分类
医药卫生引用本文复制引用
董燕,荆山,孙建伟,余泽,胡晓华..卒中后发生抑郁的相关因素探讨[J].武警医学,2015,(1):56-59,4.基金项目
浙江省医药卫生科学研究基金 （）
