武警医学Issue(2):133-135,3.
血清心型脂肪酸结合蛋白对非 ST段抬高急性冠脉综合征的诊断意义
Diagnostic value of heart-type fatty-acid binding protein in serum for non-ST-elevation a-cute coronary syndromes
摘要
Abstract
Objective To study the diagnostic value of serum heart-type fatty-acid binding protein ( H-FABP) for non-ST-ele-vation acute coronary syndromes ( NSTE ACS) .Methods H-FABP and cTnI were measured and compared in 115 NSTE ACS patients and 69 non-cardiac chest pain patients.Results The H-FABP levels were (459 ±312) pg/ml, (237 ±169) pg/ml in NSTE ACS group and non-cardiac chest pain group respectively, and there was a significant difference between the two groups (P<0.05).In NSTE ACS group, the H-FABP level of UAP group was (340 ±285) pg/ml which was lower than NSTE AMI group (592 ±289) pg/ml, and there was a significant difference between the two groups (P<0.05).For the diagnosed NSTE AMI, the area under the ROC curve of H-FABP was 0.863, the sensitivity was 97.1%, specificity was 47.6%;while for the cTnI were 0.799, 61.2%, 93.9%. Conclusions H-FABP is a highly sensitivie marker of the early NSTE ACS and H-FABP detection is conducive to diagnosis of NSTE ACS.关键词
非ST段抬高急性冠脉综合征/心型脂肪酸结合蛋白Key words
non-ST-elevation acute coronary syndrome/heart-type fatty-acid binding protein引用本文复制引用
喻红波,刘阳,罗俊卿,刘新国,简明,黄美良,罗旦,李学锋..血清心型脂肪酸结合蛋白对非 ST段抬高急性冠脉综合征的诊断意义[J].武警医学,2015,(2):133-135,3.基金项目
湖南省科技厅科技计划基金 ()