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血清心型脂肪酸结合蛋白对非 ST段抬高急性冠脉综合征的诊断意义

喻红波 刘阳 罗俊卿 刘新国 简明 黄美良 罗旦 李学锋

武警医学Issue(2):133-135,3.
武警医学Issue(2):133-135,3.

血清心型脂肪酸结合蛋白对非 ST段抬高急性冠脉综合征的诊断意义

Diagnostic value of heart-type fatty-acid binding protein in serum for non-ST-elevation a-cute coronary syndromes

喻红波 1刘阳 1罗俊卿 2刘新国 3简明 4黄美良 1罗旦 1李学锋4

作者信息

  • 1. 410006 长沙,武警湖南总队医院检验科
  • 2. 410006 长沙,武警湖南总队医院院部
  • 3. 410006 长沙,武警湖南总队医院特诊科
  • 4. 410006 长沙,武警湖南总队医院医务处
  • 折叠

摘要

Abstract

Objective To study the diagnostic value of serum heart-type fatty-acid binding protein ( H-FABP) for non-ST-ele-vation acute coronary syndromes ( NSTE ACS) .Methods H-FABP and cTnI were measured and compared in 115 NSTE ACS patients and 69 non-cardiac chest pain patients.Results The H-FABP levels were (459 ±312) pg/ml, (237 ±169) pg/ml in NSTE ACS group and non-cardiac chest pain group respectively, and there was a significant difference between the two groups (P<0.05).In NSTE ACS group, the H-FABP level of UAP group was (340 ±285) pg/ml which was lower than NSTE AMI group (592 ±289) pg/ml, and there was a significant difference between the two groups (P<0.05).For the diagnosed NSTE AMI, the area under the ROC curve of H-FABP was 0.863, the sensitivity was 97.1%, specificity was 47.6%;while for the cTnI were 0.799, 61.2%, 93.9%. Conclusions H-FABP is a highly sensitivie marker of the early NSTE ACS and H-FABP detection is conducive to diagnosis of NSTE ACS.

关键词

非ST段抬高急性冠脉综合征/心型脂肪酸结合蛋白

Key words

non-ST-elevation acute coronary syndrome/heart-type fatty-acid binding protein

引用本文复制引用

喻红波,刘阳,罗俊卿,刘新国,简明,黄美良,罗旦,李学锋..血清心型脂肪酸结合蛋白对非 ST段抬高急性冠脉综合征的诊断意义[J].武警医学,2015,(2):133-135,3.

基金项目

湖南省科技厅科技计划基金 ()

武警医学

OACSTPCD

1004-3594

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