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Duchenne型肌营养不良患儿营养状况及其影响因素的相关性

李丽 牟瑛 孙岩峰 李卉

武警医学Issue(5):460-462,465,4.
武警医学Issue(5):460-462,465,4.

Duchenne型肌营养不良患儿营养状况及其影响因素的相关性

Nutritional assessment and influencing factors in children with Duchenne muscular dys-trophy:a relevant study

李丽 1牟瑛 2孙岩峰 3李卉1

作者信息

  • 1. 100039 北京,武警总医院 营养科
  • 2. 100039 北京,武警总医院 儿科
  • 3. 100032北京,解放军302医院营养科
  • 折叠

摘要

Abstract

Objective To investigate the relationship between nutritional status and influencing factors of children with Duch-enne muscular dystrophy ( DMD) , providing the basis for nutritional and integrated caring of this disease.Methods The study included 154 children with DMD who received treatments at the Department of Neurology of the General Hospital of the Chinese People’ s Armed Police Force along with outpatient clinics from 2013 through 2014.Z-scores ( WAZ, HAZ, WHZ and BAZ) were calculated, ttest and Spearman rank correlation analysis were conducted between Z-scores and influencing factors.Results In Z-scores, means of both WHZ and BAZ were positive, while those of both WAZ and HAZ were negative.Growth retardation was present at the early stage of walking ( <9 year-old);there was a high incidence of low body weight and growth retardation ( P<0.05) till the late stage of walking (>9 year-old).For children with DMD, incidence rates of low body weight, growth retardation, emaciation and obesity were 4.6%, 20.1%, 3.9%and 13.0%, respectively.Especially, children at the early stage of walking had a high incidence of obesity (16.9%), while the incidence of growth retardation was up to 30.8%in those at the late stage of walking.Z-scores correlated with some influencing factors, WAZ and HAZ and family monthly income was positively related among them ( P<0.05) .Conclusions The nutritional status in chil-dren with DMD is unoptimistic with Z-scores at a low level;positive measures should be taken to allow clinicians and children’ s parents to improve the knowledge of the nutritional therapy for DMD, providing a good basis for sequential treatment of this disease.

关键词

肌营养不良,杜氏/营养状况/Z评分

Key words

Duchenne/muscular dystrophy/nutritional status/Z score

分类

医药卫生

引用本文复制引用

李丽,牟瑛,孙岩峰,李卉..Duchenne型肌营养不良患儿营养状况及其影响因素的相关性[J].武警医学,2015,(5):460-462,465,4.

基金项目

武警总医院重点课题项目 ()

武警医学

OACSTPCD

1004-3594

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