物理化学学报Issue(7)：1363-1369,7.DOI:10.3866/PKU.WHXB201405063
无种子法纳米金棒的制备及其对肿瘤细胞光热治疗效应研究
Seedless Synthesis of Gold Nanorods and Applications in Photo-Thermal Cancer Therapy
摘要
Abstract
We report the synthesis of gold nanorods with a simple and efficient seedless method. By changing the experimental conditions, the longitudinal absorption peak of the gold nanorods can be shifted from the visible to the near-infrared region. Mercaptopolyethylene glycol (PEG-SH) was then used to substitute cetyltrimethyl ammonium bromide (CTAB) to improve the biocompatibility of the gold nanorods. A strong inhibition of cancer cellgrowth was observed with the modified gold nanorods under near-infrared (NIR) light irradiation. Our results wil be helpful for the potential applications of gold nanorods in clinical photo-thermal cancer therapy.关键词
纳米金棒/等离子共振吸收/生物相容性/表面修饰/热疗Key words
Gold nanorod/Plasmon resonance absorption/Biocompatibility/Surface functionalization/Hyperthermia分类
化学化工引用本文复制引用
王新环,韩秋森,李婧影,杨蓉,刁国旺,王琛..无种子法纳米金棒的制备及其对肿瘤细胞光热治疗效应研究[J].物理化学学报,2014,(7):1363-1369,7.基金项目
The project was supported by the National Natural Science Foundation of China (21261130090,21073047) and Special Fund for Pilot Technology of Chinese Academy of Sciences (XDA09030303).国家自然科学基金(21261130090,21073047)和中国科学院先导科技专项(XDA09030303)资助项目 （21261130090,21073047）
