现代妇产科进展Issue(8)：635-638,4.DOI:10.13283/j.cnki.xdfckjz.2014.08.010
以直径2 cm作为临界标准行保留生育功能治疗早期宫颈癌局部肿瘤疗效的Meta分析
A Meta analysis of 2 cm as critical standard lines retain local tumor of early stage cervi-cal tumor treated by fertility-sparing surgery
闫洪亮 1吴维光 2王筝 1葛红雨3
作者信息
- 1. 河北联合大学，唐山 063000
- 2. 武警后勤学院附属医院，天津 300162
- 3. 天津市北辰区妇女儿童保健中心，天津 300400
- 折叠
摘要
Abstract
Objective:To explore the safety of cervical cancer in stage Ι ~Ⅱ with tumor size >2cm treated by fertility-sparing surgery. Methods:Search the database such as Pubmed,Medline, CBMdatabase, and VIP, CNKI website, collected the controlled trials about cervical cancer in stage Ι~Ⅱ with tumor in different size ( taking 2 cm as the boundaries ) treated by fertility-sparing surgery. screening studies that met the inclusion criteria,to evaluate its quality. All the data were analyzed by Revman 5. 0 software. Results:A total of 11 random-ized controlled trials including 1052 patients were screened. Statistically significant differences were observed in recurrence rate,the group with tumor lager than 2cm was higher than the otherˊs(OR=0. 07,95%CI 0. 04~0. 13,P<0. 00001). Conclusion:Tumor size >2cm is a risk fac-tor of early cervical cancer treated by fertility-sparing surgery. If patients with early cervical cancer >2cm who strongly wish to preserve their fertility, fertility-sparing surgery maybe a choice but cannot replace the traditional radical hysterectomy ( radical hysterectomy RH ) and pelvic lymph node dissection.关键词
早期宫颈癌/肿瘤直径/保留生育功能/Meta分析Key words
Early stage cervical tumor/Tumor size/Fertility-sparing surgery/Meta-a-nalysis分类
医药卫生引用本文复制引用
闫洪亮,吴维光,王筝,葛红雨..以直径2 cm作为临界标准行保留生育功能治疗早期宫颈癌局部肿瘤疗效的Meta分析[J].现代妇产科进展,2014,(8):635-638,4.
