现代妇产科进展Issue(4)：287-289,3.DOI:10.13283/j.cnki.xdfckjz.2015.04.013
妊娠糖尿病母亲血清视黄醇结合蛋白4水平与巨大儿发生率的相关性研究
Study on the correlation between serum RBP4,GDM and the the incidence of macroso-mia
胡矩锋 1马玉燕2
作者信息
- 1. 山东大学医学院，济南 250012
- 2. 山东大学齐鲁医院妇产科，济南 250012
- 折叠
摘要
Abstract
Objective:To explore the relationship between gestational diabetes mellitus (GDM),serum retinol binding protein 4 (RBP4) and macrosomia (MS). Methods:46 cases of GDM maternal were selected as the observation group,16 cases with macrosomia ( weight>4000g) and 30 cases with normal children. 454 cases of normal glucose tolerance (NGT) were selected as the control group,37 cases with macrosomia and 417 cases with normal children. The level of RBP4 was tested by using ELISA method. The correlation between GDM and RBP4 of macrosomia was found out by using statistical method. Results:The macrosomia incidence of the GDM group was significant higher than that of the NGT group(P<0. 05). The mean level of serum RBP4 of the pregnant women with macrosomia was higher than that of the pregnant women with normal newborns,with significant difference(P<0. 05). There was a positive corre-lation between the RBP4 and the weight of newborns(P<0. 05). Conclusion:GDM has a great influence on the incidence of macrosomia. There is a positive correlation between RBP4 and the incidence of macrosomia.关键词
妊娠糖尿病/视黄醇结合蛋白4/巨大儿Key words
Gestational diabetes mellitus/Retinol binding protein 4/Macrosomia分类
医药卫生引用本文复制引用
胡矩锋,马玉燕..妊娠糖尿病母亲血清视黄醇结合蛋白4水平与巨大儿发生率的相关性研究[J].现代妇产科进展,2015,(4):287-289,3.
