摘要
Abstract
BACKGROUND:With the development of the basic research and clinical application, as wel as stent materials, endovascular stent therapy has been widely used in cerebrovascular disease treatment. OBJECTIVE:To review the characteristics and clinical application of several kinds of stent materials. METHODS: A computer-based search of CNKI, Wanfang, and PubMed databases was performed for relevant articles published before Match 2014 using the keywords of “cerebrovascular disease, stents, biocompatibility” in Chinese and English. RESULTS AND CONCLUSION:According to release methods, cerebrovascular stents can be divided into baloon expanding stents and self-expanding stents. The original materials are mainly bare metal materials, made of memory aloy, medical stainless steel, tantalum, cobalt, nickel and titanium aloy. Because the metalic stent after implantation wil release metal ions that are easy to cause thrombosis and the restenosis rate is high, the coating stents and covered stents appear. Perioperative complications of stent implantation mainly include excessive perfusion syndrome, acute thrombosis, and vascular rupture and distal vascular embolization, vasospasm and puncture-related complications; the long-term complications are mainly restenosis after stent implantation. With the continuous improvement of stent materials and production techniques, vascular stent implantation wil be more safe and effective.关键词
生物材料/材料相容性/脑血管/支架置入/支架材料/生物相容性Key words
cerebrovascular trauma/stents/review分类
医药卫生
