摘要
Abstract
BACKGROUND:Calcium sulfate bone substitute material has a good safety and biocompatibility, and possesses good strength after implantation to restore thoracolumbar mechanical strength and reduce vertebral height loss, and moreover, it may gradual y be degraded and absorbed. OBJECTIVE:To explore the influence of posterior pedicle screw fixation combined with calcium sulfate bone substitute material on the recovery of vertebral height after thoracolumbar vertebral compression fractures. METHODS:Forty-two patients with thoracolumbar vertebral compression fractures (T12-L3) were enrol ed to receive posterior pedicle screw fixation combined with calcium sulfate bone substitute, including 27 males and 15 females, aged 21-57 years. Al patients were fol owed-up for 12 months, and then anterior vertebral height, kyphosis Cobb angle, Oswestry disability index score and visual analog scale score before and after treatment were determined and compared. RESULTS AND CONCLUSION:At the end of fol ow-up, no local complications, no coagulation, no immune response and no screw breakage occurred;the anterior vertebral height, kyphosis Cobb angle, Oswestry disability index score and visual analog scale score were significantly improved (P<0.05). These findings indicate that the posterior pedicle screw fixation combined with calcium sulfate bone substitute can restore the vertebral height and promote functional recovery of patients with thoracolumbar vertebral compression fractures.关键词
生物材料/骨生物材料/硫酸钙骨替代材料/胸腰椎骨折/压缩性骨折/经椎弓根/椎体高度Key words
Calcium Sulfate/Fractures, Compression/Pain Measurement分类
医药卫生
