中国组织工程研究Issue(25)：4069-4075,7.DOI:10.3969/j.issn.2095-4344.2015.25.026
钛合金表面抗菌涂层：抗菌能力及生物相容性
Titanium surface covered with antimicrobial coating:antibacterial ability and biocompatibility
王家琦 1尚剑 1孙晔 2韩昕光1
作者信息
- 1. 哈尔滨医科大学附属第一医院骨外科，黑龙江省哈尔滨市 150001
- 2. 哈尔滨工业大学，黑龙江省哈尔滨市 150001
- 折叠
摘要
Abstract
BACKGROUND:Titanium al oy with good biocompatibility, corrosion resistance and mechanical properties have been widely used in clinic. How to give its excel ent antibacterial properties so as to cope with plant-associated infections has become a research focus in recent years. OBJECTIVE:To review the principle, techniques, classification and relative merits of antimicrobial coating. METHODS:A computer-based search of Scopus database and VIP database was performed by the first author to retrieve relevant articles published from January 1990 to January 2014 using the keywords of“titanium al oy, plant, antibacterial, coating”. RESULTS AND CONCLUSION:Coatings can be classified into antibiotic coating, non-antibiotic organic antimicrobial coating, inorganic antibacterial coating, anti-adhesion coating, antibacterial bioactive polymer coating, al of which have better biocompatibility, but also have their limitations. Current studies concerning antimicrobial coatings mainly focus on how to enhance the binding force between antimicrobial coating and the substrate as wel as how to get a good anti-bacterial ability, biocompatibility, high wear resistance and persistence;antibacterial phase structure and distribution effects on the bacterial colonization. The antibacterial phase structure and distribution is the key factor for the antimicrobial properties of titanium al oys with either entirely added anti-bacterial elements or surface coating.关键词
生物材料/骨生物材料/钛合金/内植物/抗菌/涂层Key words
Biocompatible Materials/Titanium/Polymers分类
医药卫生引用本文复制引用
王家琦,尚剑,孙晔,韩昕光..钛合金表面抗菌涂层：抗菌能力及生物相容性[J].中国组织工程研究,2015,(25):4069-4075,7.
