中国组织工程研究Issue(29)：4715-4720,6.DOI:10.3969/j.issn.2095-4344.2015.29.024
应力在肌腱愈合中的作用
Stress in tendon healing
摘要
Abstract
BACKGROUND:As mechanical load-bearing tissues, tendons have unique biomechanical characteristics. Mechanical loading is necessary in tendon development, and the tendon can alter its structure and biological behaviors in response to the various mechanical loading conditions. OBJECTIVE: To fuly understand the healing process and biomechanical properties of the damaged tendon so as to know the researching progress in the role of stress in the tendon healing process. METHODS: An electronic search of Chinese Biomedical Literature Database and PubMed databases was done for colection of reviews and papers addressing stress effects on tendon healing, and then we analyzed the role of stress in the healing process of tendon from the micro and macro levels. RESULTS AND CONCLUSION:Totaly 59 relevant articles were enroled. Tendon is sensitive to stress, and it can change its structure and biological reaction in response to different stress loadings. Proper stress stimulus to the tendon is necessary to the tendon development and healing. How to achieve a good balance between the lowest (resulting in alienation effect) and the highest stress loadings (resulting in minimaly invasive injury) during the clinical tendon healing is a chalenge. At present the treatment of tendon injuries is stil a huge chalenge to clinicians, and the vast majority of tendon injuries belong to tissue healing.关键词
组织构建/组织工程/应力/肌腱/肌腱细胞/肌腱损伤/肌腱愈合/肌腱粘连/生化特性/生物力学/国家自然科学基金Key words
Stress, Mechanical/Tendon Injuries/Tissue Adhesions分类
医药卫生引用本文复制引用
郭文,王继宏,温树正,许鹏成..应力在肌腱愈合中的作用[J].中国组织工程研究,2015,(29):4715-4720,6.基金项目
国家自然科学基金应急管理项目(81441117) （81441117）
