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689株鲍曼不动杆菌的临床分布及耐药性分析

张志强 陈国强 曹海燕

现代医院Issue(7):4-6,9,4.
现代医院Issue(7):4-6,9,4.DOI:10.3969/j.issn.1671-332X.2014.07.002

689株鲍曼不动杆菌的临床分布及耐药性分析

DISTRIBUTION AND DRUG RESISTANCE OF 689 STRAINS OF ACINETOBACTER BAU-MANNII

张志强 1陈国强 1曹海燕1

作者信息

  • 1. 惠州市中心人民医院 广东惠州516001
  • 折叠

摘要

Abstract

Objective To explore the distribution of Acinetobacter baumannii and its drug resistance to 17 antimicro-bial agents to provide basis for clinical treatment.Methods The data of 689 strains of A.baumannii from Jan.2010 to Dec. 2012 were collected and reviewed for bacterial identification and drug sensitive test and then analyzed using WHONET 5.4. Results 689 strains of A.baumannii isolates were broadly distributed in sputum (75.5%), most primarily isolated from the ICU (36.9%).The antimicrobial susceptibility testing showed that the drug resistance rate of Ab was the highest to Bactrim (36.3%), followed by gentamicin (29.0%), and the lowest to cefperazone-sulbactam (8.0%).The drug resistance rate of Ab to cefperazone-sulbactam was the lowest (8.5%) in 2012.In the three years, the drug resistance rate of Ab to imipenem was the biggest rise (14.5%);while to gatifloxacin and levofloxacin declined.The drug resistance rate of Ab to gatifloxacin dropped by 13.1%, which was bigger than that to levofloxacin (9.5%).The drug resistance rates of Ab to the rest antimi-crobial agents fluctuated insignificantly, but were all in an increasing trend.Conclusion Acinetobacter baummannii mainly distribute in sputum of patients in the ICU and department of respiratory diseases, and its detection rate and drug resistance rate are increasing year by year.

关键词

鲍曼不动杆菌/感染/耐药率

Key words

Acinetobacter baumannii/Infection/Drug resistance rate

引用本文复制引用

张志强,陈国强,曹海燕..689株鲍曼不动杆菌的临床分布及耐药性分析[J].现代医院,2014,(7):4-6,9,4.

现代医院

1671-332X

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