现代医院Issue(8)：152-154,3.DOI:10.3969/j.issn.1671-332X.2014.08.063
清远市中心区域妇女人乳头瘤病毒感染现状调查与分析
THE INVESTIGATION OF PRESENT SITUATION OF HUMAN PAPILLOMAVIRUS INFEC-TION OF WOMEN IN PARTS OF QINGYUAN CITY GUANGDONG PROVINCE
摘要
Abstract
Objective To investigate the distribution of different Human papillomavirus ( HPV) subtype infection of women in parts of Qingyuan City Guangdong Province .In order to offer some evidences for the prevention and treatment of the cervical cancer in the region.Methods Flow-through hybridization and gene chip ( HybriMax) were utilized to detect 21 different subtypes of HPV from low genitalia in 23 983 patients.And some of positive samples were checked for liquid -based pap test(LPT) and(or) biopsy by the vaginoscope.Results 5 372 positive samples were detected, occupying 22.40%in to-tal (5 372/23 983) and covering all 21 genotypes.The order of prevalence rates from high to low were HPV-16(6.02%)、52(4.46%)、56(2.68%)、11(2.25%)、66(1.86%).In 5 372 positive samples, mono-infections account for 3 966, reaching 73.83%;the rest are multiple infections.The peak age of HPV infection ranged from 26 to 45 years old.The rate of high-risk HPV infections were increased with the higher severity of cervical dysplasia , there were all 100%for CINⅡ、CINⅢand invasive cervix carcinoma. Conclusion HPV prevalence is at a high level in woman in Qingyuan region .All 21 genotypes were found in HPV infective women, and majority infection was HPV -16、52、56.HPV infection often occurs in young and middle -age women.There is a close relation between HPV infection and cervix diseases.Cervical carcinoma would caused by HPV infec-ting.Long-time following-up visit for HPV infected patients will reduces the incidence of cervical carcinoma.关键词
人乳头瘤病毒/基因分型/宫颈疾病Key words
Human papillomavirus (HPV)/Genotype detection/Cervical diseases引用本文复制引用
黄振勇,李介华,吴爱娟,胡庆兰,岑欢,周艳..清远市中心区域妇女人乳头瘤病毒感染现状调查与分析[J].现代医院,2014,(8):152-154,3.基金项目
清远市科技计划项目 （）
