现代医院Issue(3):27-28,32,3.DOI:10.3969/j.issn.1671-332X.2015.03.007
治疗性白细胞单采术在高白细胞白血病治疗中的应用
THE APPLICATION OF THERAPEUTIC LEUKAPHERESIS IN THE TREATMENT OF HYPER-LEUKOCYTIC LEUKEMIA
严仲文 1叶惠芬 1周碧容 2蒋友明 3曾少平4
作者信息
- 1. 东莞市中心血站 广东东莞 523000
- 2. 深圳市坪山新区人民医院 广东深圳 518118
- 3. 东莞市厚街医院 广东东莞 523000
- 4. 东莞市三局医院 广东东莞 523000
- 折叠
摘要
Abstract
Objective To investigate the curative effect of leukocyte apheresis in the treatment of hyperleu -kocytic leukemia .Methods 28 patients with hyperleukocytic leukemia received leukocyte apheresis for 45 timesusing MCS+blood cell separator , with white blood cell suspension from 300 to 500 mL removed every time .The white blood cells ( WBC) ,hemoglobin ( Hb) , platelet ( Plt) changes after operation , and the clinical symptoms , signs im-provement were improved .Results After apheresis , WBC count in peripheral hemogram were decreased significant-ly, Plt count significantly lowered , but there was no significant change in Hb .The symptoms of the disease were re-lieved.Conclusion Leukocyte apheresis , as a scientific and safe therapy , can quickly reduce the tumor burden and shorten the remission induction time in the treatment of hyperleukocytosis leukemia .关键词
白细胞单采术/高白细胞白血病/外周血象Key words
Leukocyte apheresis/Hyperleukocytic leukemia/Peripheral hemogram引用本文复制引用
严仲文,叶惠芬,周碧容,蒋友明,曾少平..治疗性白细胞单采术在高白细胞白血病治疗中的应用[J].现代医院,2015,(3):27-28,32,3.