现代医药卫生Issue(10)：1441-1442,1445,3.DOI:10.3969/j.issn.1009-5519.2014.10.001
多发性骨髓瘤免疫球蛋白M蛋白测定的结果分析
Results analysis of IgM protein detection of multiple myeloma
摘要
Abstract
Objective To retrospectively analyze the detection results of serum immunofixation electrophoresis (IFE) and serum immunoglobulin M of 63 patients with multiple myeloma (MM),and investigate the application of M protein in the diag-nosis of MM. Methods A total of 63 patients diagnosed with MM ,including 50 cases with the age of 55 years or older and 8 cas-es with the age less than 50 years and the proportion of male to female was 41∶22,were selected to conduct IFE,serum protein electrophoresis and quantitative determination of immunoglobulin. The results were analyzed and compared. Results The pa-tients with IgG had the highest proportion accounting for 68.3%(43/63),and the free light chain MM was the lowest accounting for 9.5%(6/63). Whateverκ-type M protein orλ-type M protein,the ratio ofκ/λwas significantly abnormal. The positive rate of M protein was highest by serumκ/λaccounting for 84.1%(53/63),while lowest by serum immunoglobulin quantitative minimum ac-counting for 39.7%(25/63). Conclusion Classifications and types of M protein provide valuable basis for the diagnosis and treatment of MM clinically.关键词
多发性骨髓瘤/免疫球蛋白类/分析/免疫球蛋白A/分析/免疫球蛋白G/分析/免疫球蛋白M/分析/免疫电泳/血蛋白电泳Key words
Multiple Myeloma/Immunoglobulins/alysis/Immunoglobulin A/alysis/Immunoglobulin G/alysis/Immunoglobulin M/alysis/Immunoelectrophoresis/Blood protein electrophoresis引用本文复制引用
蔡惠兴,苏荣,黄慧萍,钟敏仙,陈胜男,谢湘媚,卓雪芽..多发性骨髓瘤免疫球蛋白M蛋白测定的结果分析[J].现代医药卫生,2014,(10):1441-1442,1445,3.基金项目
2014年广东省佛山市卫生局医学科研课题（2014127）。 （）
