现代医药卫生Issue(14)：2109-2110,2112,3.DOI:10.3969/j.issn.1009-5519.2014.14.012
以抗利尿激素分泌不当综合征为首发表现的吉兰-巴雷综合征荟萃分析
Meta-analysis of Guillain-Barré syndrome with SIADH as the initial presentation
摘要
Abstract
Objective To summarize the clinical characteristics and management of Guillain-Barre syndrome(GBS) with syndrome of inappropriate antidiuretic hormone(SIADH) as the initial presentation. Methods A systematic retrieval of GBS with SIADH as the initial presentation in 1980-2014 was performed. The patients in the study were analyzed to explore the clinical characteristics. Results All the 4 patients were females,and the age of onset was from 38 to 82 years old with a median age of 62.5 years. The main symptoms and signs in the early stages of disease included altered mental status (100%),headache (50%),malaise(50%),back pain(50%),no response to voice(25%),vomiting(25%) and so on. Physical examination showed that nervous system impairment had no obvious locating features (75%). The interval time between the onset and the day on which typical symptoms of GBS appeared,varied from 3 to 15 d,with a median time of 5 d. Conclusion Pathogenesis of this disease is still not clear,it often appears with severe and complicated clinical situations,which is difficult to diagnose. Malignant tumor screening is needed to exclude the possibility that paraneoplastic syndrome.关键词
ADH分泌不当综合征/低钠血症/格林-巴利综合征/疾病特征/Meta分析Key words
Inappropriate ADH syndrome/Hyponatremia/Guillain-Barre syndrome/Disease attributes/Meta-Analysis引用本文复制引用
刘耀文..以抗利尿激素分泌不当综合征为首发表现的吉兰-巴雷综合征荟萃分析[J].现代医药卫生,2014,(14):2109-2110,2112,3.
