现代医药卫生Issue(17)：2577-2579,3.DOI:10.3969/j.issn.1009-5519.2014.17.008
低场MRI诊断阿尔茨海默病与血管性痴呆所致认知功能障碍的对比研究
Comparative analysis of cognitive dysfunction induced caused by Alzheimer′s disease and vascular dementia through di-agnosis of low-field MRI performance
詹孔才 1陈霞 1蒋硕 1贺友才 2龚飞中1
作者信息
- 1. 自贡市精神卫生中心，四川自贡643020
- 2. 自贡市第四人民医院，四川自贡643020
- 折叠
摘要
Abstract
Objective To analyze the magnetic resonance imaging (MRI) expressions of Alzheimer′s disease (AD) and vascular dementia(VD),and explore the role of MRI in differential diagnosis of dementia. Methods A total of 81 patients with dementia,who were treated in the hospital in 2011-2013,were selected as research objects,including 41 cases of AD(AD group) and 40 cases of VD(VD group). To compare and analyze the proportion of hippocampal atrophy,encephalatrophy,ventricular changes, cerebral infarction,cerebral hemorrhage,brain myelin changes and normal by MRI performance in AD group and VD group. Re-sults The results showed that the patients′hippocampal volume in AD group was smaller than that in VD group ,and cerebral at-rophy in temporal and parietal was more obvious in AD group as well;VD could be divided into multi-infarct dementia(MID) and subcortical arteriosclerotic encephalopathy(Binswanger′s dementia,BD),the former showed bilateral centrum semiovale and symmetric or asymmetric patchy cerebral white matter degeneration in bilateral basal ganglia and paraventricle white matter , while the latter showed whole or focal brain atrophy. Conclusion According to the imaging characteristic of MRI in difference areas of brain between AD and VD,combination with clinical manifestations is beneficial to the differential diagnosis of AD and VD.关键词
阿尔茨海默病/痴呆,血管性/磁共振成像/认知障碍/脑梗死Key words
Alzheimer disease/Dementia,vascular/Magnetic resonance imaging/Cognition disorders/Brain infarction引用本文复制引用
詹孔才,陈霞,蒋硕,贺友才,龚飞中..低场MRI诊断阿尔茨海默病与血管性痴呆所致认知功能障碍的对比研究[J].现代医药卫生,2014,(17):2577-2579,3.
