现代医药卫生Issue(17)：2582-2583,2586,3.DOI:10.3969/j.issn.1009-5519.2014.17.010
高危因素对葡萄胎后恶变的影响临床分析
Clinical analysis of high-risk factors on malignant transformation of hydatidiform mole
摘要
Abstract
Objective To analyze the clinical features of hydatidiform mole patients with high-risk factors,in order to provide reference for improving the diagnosis of the gestational trophoblastic tumor (GTN). Methods A retrospective analysis was conducted on clinical data of 162 hydatidiform mole patients ,who were diagnosed after uterine curettage by pathological ex-amination in the Obstetrics Department of the hospital from January 2007 to December 2013. To observe the clinical manifesta-tions of GTN,therapeutic effect and so on,and compare the clinical features of hydatidiform mole patients with and without high-risk factors. Results Amon the 162 patients with hydatidiform mole,46 cases had malignant transformation,including 36 cases with high-risk factors and 10 cases without high-risk factors. The malignant transformation rate,clinical manifestation and thera-peutic effects between the two kinds of patients were compared ,and the comparison on malignant transformation rate and clinical manifestation between the patients with high-risk factors and patients without high-risk factors had statistically significant differ-ence (P<0.05);the therapeutic effects of GTN patients after mole treatment between the two kinds patiens had no statistically sig nificant difference(P>0.05). Conclusion The malignant transformation rate of hydatidiform mole patients is related with age of onset,uterine size,ovarian lutein cysts and other factors,so proper evaluation to the high-risk factors has certain guidance for early prevention of hydatidiform mole in clinical and preventive chemotherapy ,and it also benefits to diagnose of GTN and improve clinical efficacy.关键词
葡萄胎/恶变/危险因素/妊娠滋养细胞肿瘤Key words
Hydatidiform mole/Malignant transformation/Risk factors/Gestational trophoblastic neoplasms引用本文复制引用
梁哨雅..高危因素对葡萄胎后恶变的影响临床分析[J].现代医药卫生,2014,(17):2582-2583,2586,3.
