现代医药卫生Issue(10)：1448-1449,1452,3.DOI:10.3969/j.issn.1009-5519.2015.10.003
自拟热哮宁汤对支气管哮喘急性发作期患者血清TXB2和6-ket-PGF-1α水平的影响
Effect of self-made Rexiaoning Decoction on serum TXB2,6-ket-PGF-1αlevel of bronchial asthma patients in acute attack
摘要
Abstract
Objective To observe the effect of self-made Rexiaoning decoction uniting conventional therapy on serum thromboxane B2 (TXB2) and 6-ket-PGF-1αof bronchial asthma patients in acute attack,i.e. heat asthma patients. Methods Randomly divided 96 selected bronchial asthma patients in acute attack (i.e. heat asthma patients) into two groups,48 in each. Gave bronchodilators and steroid hormone as basic conventional therapy to both groups ,while adding Rexiaoning decoction to treatment group. Judged the clinical therapeutic effect by determining pulmonary ventilation functions before treatment and after three days of treatment. Also used enzyme linked immunosorbent assay to determine TXB2 and 6-ket-PGF-1αlevel. Results The total control rate of treatment group was clearly higher than that of control group,difference showing statistic significance(P<0.05). Treatment group prominently reduced TXB2 and rose 6-ket-PGF-1αlevel comparing to control group,difference showing statistic significance(P<0.05). Conclusion The clinical therapeutic effect of Rexiaoning decoction uniting conventional therapy is better than just using conventional therapy on bronchial asthma patients in acute attack ,i.e. heat asthma patients. It is more likely to im-prove TXB2 and 6-ket-PGF-1αcytokines secreting and can be used as an important method to treat bronchial asthma patients in acute attack.关键词
哮喘/血栓烷B2/血液/6-酮前列腺素F1α/血液/热哮宁汤Key words
Asthma/Thromboxane B2/blood/6-ketoprostaglandin F1 alpha/blood/Rexiaoning decoction引用本文复制引用
胡赛,黄艳,吴小宁..自拟热哮宁汤对支气管哮喘急性发作期患者血清TXB2和6-ket-PGF-1α水平的影响[J].现代医药卫生,2015,(10):1448-1449,1452,3.基金项目
湖南省中医药科研计划项目（201251）。 （）
