现代医药卫生Issue(11):1619-1620,1623,3.DOI:10.3969/j.issn.1009-5519.2015.11.007
抗病毒治疗483例艾滋病患者生存分析
Survival analysis of 483 AIDS patients′antiviral therapy
摘要
Abstract
Objective To understand the basic characteristics and survival time of patients receiving highly active anti-retroviral therapy(HAART),and to analyze the main risk factors affecting the survival time. Methods Collected data in the na-tional AIDS comprehensive data information system from January to June ,2014. Retrospectively observed previous patients′sur-vival time and used SPSS18.0 statistical software to do data analysis. Results There were 49 death cases in 483 AIDS patients. The mortality was 10.14%(49/483). The survival rate was 0.94%,0.92%,0.88%,0.87%,0.82%,0.80%after 0.5,1.0,2.0, 3.0,4.0,5.0 years of treatment. 51.02% (25/49) of the patients died within 6 months after the treatment. Patients′survival time was affected by age,route of infection,baseline CD4+T cell value,symptoms and signs. Conclusion The precautions and antivi-ral therapy should be reinforced when patients are old,taking drugs,have low immune function,and the symptoms already appear. This is to further increase AIDS patients′survival rate and extend their survival time.关键词
获得性免疫缺陷综合征/药物疗法/抗逆转录病毒治疗,高效/存活率分析/预后Key words
Acquired immunodeficiency syndrome/drug therapy/Antiretroviral therapy,highly active/Survival analysis/Prognosis引用本文复制引用
张臻,李向东,周超,汪强,曾艺..抗病毒治疗483例艾滋病患者生存分析[J].现代医药卫生,2015,(11):1619-1620,1623,3.基金项目
中国-默沙东艾滋病防治合作项目(二期);重庆市卫生局2013年医学科研计划项目(2013-2-148)。 ()