摘要
Abstract
Objective To discuss the clinical application effect of target controlled infusion (TCI) in elderly patients un-dergoing painless colonoscopy. Methods 80 elderly patients undergoing painless colonoscopic examination and treatment in our hospital from May to September 2014 were selected and randomly divided into the TCI group (group T)and the manual infusion group(group M),40 cases in each group. The anesthesia in the group T:fentanyl 0.03-0.05 mg by intravenous injection and propofol plasma target concentration was set at 3μg/mL;which in the group M:fentanyl 0.03-0.05 mg and propofol 1.0-1.5 mg/kg by in-travenous injection in turn. The colonoscopic examination and treatment were started after the patients in both two groups fell asleep and eyelash reflex disappeared. The changes of SBP,DBP,HR,RR and SpO2 before medication,at 2 min after medication, immediately colonoscopy,at 5,8,10 min after colonoscopy were recorded;the consciousness disappearance time,awakening time,leaving hospital time,adverse reactions and propofol dosage were recorded too. Results HR and SpO2 at 2 min after medi-cation had statistical differences between the two groups (P<0.05);DBP and HR at 5 min after colonoscopy showed statistical dif-ferences between the two groups(P<0.05);the propofol dosage,intraoperative additional dose,drug effect onset time,patient′s awaken-ing time and leaving hospital time had statistical differences between the two groups (P<0.05). Conclusion TCI anesthesia is more smooth and steady,has slight hemodynamic change,short awakening time,mild respiratory depression,unobvious injection pain and few adverse reactions,and should become the mainstream clinical medication mode.关键词
结肠镜检查/二异丙酚/静脉/麻醉/靶控输注/老年人Key words
Colonoscopy/Propofol/Veins/Anesthesia/Target controlled infusion/Aged
