协和医学杂志Issue(4)：267-270,4.DOI:10.3969/j.issn.1674-9081.2015.04.006
腹腔镜切除术治疗Ⅲ期结肠癌的长期预后
Long-term Outcomes of Laparoscopic Surgery for Stage Ⅲ Colon Cancer
徐徕 1肖毅 1林国乐 1吴斌 1牛备战 1孙曦羽 1邱辉忠1
作者信息
- 1. 中国医学科学院 北京协和医学院 北京协和医院基本外科，北京100730
- 折叠
摘要
Abstract
Objective To investigate the clinical efficacy and long-term outcomes of laparoscopic radical re-section for stageⅢcolon cancer.Methods A total of 169 stageⅢcolon cancer patients treated with laparoscopic surgery (n=75) or open surgery (n=94) between January 2007 and December 2012 in Department of General Sur-gery, Peking Union Medical College Hospital were included.The clinicopathologic features, as well as long-term outcomes including 5-year local recurrence rate, overall survival, and disease-free survival, were compared between the two groups.Results Compared with the open surgery group, the laparoscopic surgery group had significantly longer operation time [ (171.3 ±43.2) minutes vs.(132.7 ±60.4) minutes, P<0.001], significantly less blood loss [ (86.3 ±61.7) ml vs.(109.8 ±74.6) ml, P=0.030], and significantly more invaded lymph nodes detec-ted (23.3 ±12.2 vs.19.3 ±9.6, P=0.022).No significant difference was found between the laparoscopic surgery group and open surgery group in cumulative local recurrence rate (6.7%vs.8.5%, P=0.876), 5-year overall survival (73.6% vs.58.8%, P=0.317), and 5-year disease-free survival (61.6% vs.56.3%, P=0.544). Conclusion Laparoscopic colectomy is safe and effective for stageⅢcolon cancer, comparable with the conven-tional open colectomy in terms of long-term oncological outcomes.关键词
Ⅲ期结肠肿瘤/腹腔镜手术/预后分析Key words
stage Ⅲ colon cancer/laparoscopic surgery/outcome analysis分类
医药卫生引用本文复制引用
徐徕,肖毅,林国乐,吴斌,牛备战,孙曦羽,邱辉忠..腹腔镜切除术治疗Ⅲ期结肠癌的长期预后[J].协和医学杂志,2015,(4):267-270,4.
