心理科学进展Issue(12)：1899-1910,12.DOI:10.3724/SP.J.1042.2014.01899
MAOA基因与抑郁的关系
Association between MAOA Gene and Depression
摘要
Abstract
The development of depression has important underpinnings. With the advancement of molecular genetics, the research on the mechanisms of depression has reached molecular level in recent years. Recent studies have demonstrated that the MAOA (monoamine oxidase A) gene has played an important role in depression. Evidence has been reported that MAOA gene had a direct effect on depression, and MAOA gene interacted with environments and other genes in predicting depression. However, the related research findings have not been always consistent and even contradictory in some cases. Future research should focus on such issues as the complex interactions between MAOA gene and multi-environments or other genes, examining the age effect of MAOA gene on depression, and its underlying neurobiological mechanisms.关键词
MAOA基因/抑郁/G×E交互作用/MAOA-uVNTRKey words
MAOA gene/depression/gene-environment interaction/MAOA-uVNTR分类
社会科学引用本文复制引用
曹丛,陈光辉,王美萍,曹衍淼,张文新..MAOA基因与抑郁的关系[J].心理科学进展,2014,(12):1899-1910,12.基金项目
国家自然科学基金项目(31271105)、高等学校博士学科点专项科研基金项目(20133704110001)、“十二五”强化建设重点学科(发展与教育心理学)建设经费资助项目。 （31271105）
