心理科学进展Issue(4)：602-613,12.DOI:10.3724/SP.J.1042.2015.00602
神经质人格的神经生理基础
Neurophysiological Mechanism of Neuroticism
摘要
Abstract
Neuroticism is a trait of personality, and its core feature is the tendency to experience negative emotions. Highly neurotic individuals had more intense emotional reactions as well as poorer performances on emotion perception and coping. Thus, these individuals tended to experience more negative emotions, leading them to be more vulnerable to a series of mental and physical disorders. Due to these factors, neuroticism has become one of the most important risk factors in development of psychopathology. Evidence from studies concerning autonomic nervous system, endocrine system, and the brain showed that highly neurotic individuals had reduced cardiovascular flexibility, enhanced HPA baseline activity, increased EEG activity, and enhanced amygdala activity induced by negative emotions. More importantly, there was evidence that the top-down and bottom-up pathway of amygdala may be the key to explain these associations. Future research is strongly encouraged to integrate methods from genetics, electrophysiology, biochemistry, and brain imaging technology, so as to construct a neuro-physiological model of neuroticism.关键词
神经质/自主神经系统/下丘脑-垂体-肾上腺皮质轴/杏仁核Key words
neuroticism/autonomic nerves system/hypothalamic-pituitary-adrenocortical axis/amygdala分类
社会科学引用本文复制引用
黄雅梅,周仁来,吴梦莹..神经质人格的神经生理基础[J].心理科学进展,2015,(4):602-613,12.基金项目
国家重点基础研究计划(2011CB505101)、北京中医药大学证候与方剂基础研究北京市重点实验室开放课题(2011-SYSKFKT03)和北京尚善公益基金会“尚善”基金资助。 （2011CB505101）
