心理科学进展Issue(6)：1000-1008,9.DOI:10.3724/SP.J.1042.2015.01000
一个测量抑郁症的重要神经指标：静息额叶脑电活动的不对称性
An Important Neural Indicator of Measuring Depression：The Asymmetry of Resting Frontal Activity
摘要
Abstract
The asymmetry of resting frontal activity was examined when differential activation of the alpha frequency band of left and right frontal cortex was found, i.e., frontal EEG lateralization. It had been showed largely that resting frontal EEG asymmetry was related to depression. Based on worldwide studies, we found that there was a negative correlation between resting frontal EEG asymmetry and depression level. Compared with individuals without depressive symptoms, those with depressive symptoms showed enhancement of right frontal activity. For depressive individuals, resting frontal EEG asymmetry was stable in the short and long run. That is to say, resting frontal EEG asymmetry predicted the risk of depression, which showed that frontal EEG asymmetry could be regarded as a neural index of depressive symptoms. In addition, resting frontal EEG asymmetry reflected the activation of dorsolateral prefrontal cortex, which might play a role in developing depressive symptoms. Future studies should focus on the neural mechanism of resting frontal EEG asymmetry predicting depression, the application of frontal EEG symmetry predicting depressive symptoms, and training methods (e.g., mindfulness training) to change the resting frontal EEG asymmetry of depressive individuals, relieving the depression level.关键词
抑郁症/额叶EEG偏侧化/额叶EEG不对称性/神经指标Key words
depression/frontal EEG lateralization/frontal EEG asymmetry/neural index分类
社会科学引用本文复制引用
刘雷,周仁来..一个测量抑郁症的重要神经指标：静息额叶脑电活动的不对称性[J].心理科学进展,2015,(6):1000-1008,9.基金项目
国家重点基础研究发展计划(批准号:2011CB711001) （批准号:2011CB711001）
中国科学院心理健康重点实验室开放课题 （）
北京尚善公益基金会“尚善”基金资助项目。 （）
