西南国防医药Issue(6)：662-665,4.DOI:10.3969/j.issn.1004-0188.2015.06.033
溶栓胶囊防治急性高原病的效果观察
摘要
Abstract
To explore the effect of Thrombolytic capsules in prevention and treatment of the acute high altitude diseases (AHAD). Total 112 army-men to be urgently deployed at the 4300 m high altitude were divided into three groups and orally took Thrombolytic capsules (group A, n = 32, 0.25 g per capsule, four capsules per time), compound rhodiola capsules (group B, n = 40, 0.38g per capsule, two capsules per time) and placebo (group C, chow mein capsules, n = 40, two capsules per time) in the morning and evening every day. The medication lasted for 15 days including three days before the deployment, four days during the deployment and eight days after the deployment at high altitude. At the 1st, 3rd, 5th and 7th day after the deployment, their SaO2 were examined and then index scores were made according to AHAD symptoms of the subjects in the follow-up notes. Comparing with group C, AHAD symptom scores and disease occurrence rates at the 3rd, 5th and 7th day in group A and B were lower, but the SaO2 was higher ( < 0.05 or < 0.01); AHAD symptom scores in group A and B had no statistic difference ( >0.05), but the AHAD occurrence rate in group A, such as palpitation, hard breathe, chest choking sense and agrypnia, was significantly lower than that in group B and C ( < 0.05 or < 0.01). Thrombolytic capsule can improve AHAD symptoms, and compared with compound rhodiolae, it can also achieve a better effect in prevention of AHAD symptoms, such as palpitation, hard breathe, chest choking sense and agrypnia, resulted from oxygen deficit.关键词
溶栓胶囊/复方红景天/急性高原病/防治Key words
thrombolytic capsule/compound rhodiolae/AHAD/prevention and treatment分类
医药卫生引用本文复制引用
崔建华,张扬,李强,吴佩锋,王福领,李彬..溶栓胶囊防治急性高原病的效果观察[J].西南国防医药,2015,(6):662-665,4.基金项目
高原医学教育部重点实验室资助项目（2011JSGY05）；兰州军区高原科研攻关课题 （）
