新医学Issue(7):459-463,5.DOI:10.3969/g.issn.0253-9802.2014.07.010
不同检测时段的瞬时弹性成像下肝硬度值变化
Changes in liver stiffness measured by transient elastography at different time points
叶一农 1李宗良 1白红莲 1龙辉 1吴有全1
作者信息
- 1. 528000 佛山,佛山市第一人民医院感染科
- 折叠
摘要
Abstract
Objective To observe the changes in the liver stiffness (LS)measured by fibroscan (FS)at different time points. Methods Transient elastography results of 4731 cases with chronic hepatopathy were retrospectively analyzed and the discrepancy among the values measured at nine time points was statistical-ly compared. LS was regarded as the dependent variable,detection time point,gender,and hospitalization or not as main effect factors and age as the covariate. Univariate analysis of covariance was performed. Results Mean LS level of all 4731 subjects was (8.8 ±8.3)kPa. The LS measured at different time points significantly differed (P<0.05). LS levels detected at 10,11,9,8 and 7 a.m. were almost similar,whereas signifi-cantly lower than those measured at 17,16,14 and 15 p.m. (all P<0.05). Gender,age and the proportion of hospitalized patients significantly differed among different time points (P<0.01 or 0.006). Detection time point,gender,hospitalization or not,and age are independent factors affecting LS levels (all P<0.01 ).These three factors equally exert a combined effect upon LS levels (P<0.01). Conclusion Detection time point probably affects the measurement of LS. Therefore,the measurement of LS should be conducted at a fixed period in the morning.关键词
瞬时弹性成像检测/肝纤维化/肝硬度Key words
Transient elastography/Liver fibrosis/Liver stiffness引用本文复制引用
叶一农,李宗良,白红莲,龙辉,吴有全..不同检测时段的瞬时弹性成像下肝硬度值变化[J].新医学,2014,(7):459-463,5.