新医学Issue(8)：512-514,3.DOI:10.3969/g.issn.0253-9802.2014.08.006
呼出气一氧化氮在预测布地奈德治疗慢性咳嗽疗效的临床价值
Clinical value of fractional exhaled nitric oxide in predicting the efficacy of pulmicort respules in treat- ment of chronic cough
王丽珍 1李斌 1王燕 1陈芳 1颜文森 1王钧1
作者信息
- 1. 510317 广州，广东省第二人民医院呼吸内科
- 折叠
摘要
Abstract
Objective Toevaluatetheclinicalvalueoffractionalexhalednitricoxide(FeNO)in predictingtheefficacyofpulmicortrespulesintreatmentofchroniccough.Methods Sixtychroniccoughpa-tients with negative results in bronchial provocation and dilation tests,induced sputum eosinophil count <3%and elevated levels of FeNO were randomly divided into the treatment (n=30)and control groups (n=30).In the control group,roxithromycin and mucosolvan were used for treatment. In the treatment group,pulmicort respulesinhalationwasperformedadditionally,2mgforeachtestfortwicedaily.Results Afteroneweek treatment,the remission rate and overall efficacy in the treatment group were significantly higher compared with those in the control group (both P<0.01 ). FeNO level in the treatment group was significantly decreased (P<0.01)whereastheFeNOlevelinthecontrolgroupdidnotdiffer(P>0.05).Conclusion FeNOplaysa role in selecting medication therapy for patients with chronic cough. Pulmicort respules inhalation is effective in treatment of chronic cough with elevated levels of FeNO.关键词
慢性咳嗽/呼出气一氧化氮/雾化吸入布地奈德Key words
Chroniccough/Fractionalexhalednitricoxide/Pulmicortrespules引用本文复制引用
王丽珍,李斌,王燕,陈芳,颜文森,王钧..呼出气一氧化氮在预测布地奈德治疗慢性咳嗽疗效的临床价值[J].新医学,2014,(8):512-514,3.
