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粪菌移植治疗炎症性肠病的现状和问题

廖诗乐 陈白莉 曾志荣

新医学Issue(9):569-572,4.
新医学Issue(9):569-572,4.DOI:10.3969/g.issn.0253-9802.2014.09.002

粪菌移植治疗炎症性肠病的现状和问题

Current situation and related problems of fecal microbiota transplantation in treatment of inflammato-ry bowel disease

廖诗乐 1陈白莉 1曾志荣1

作者信息

  • 1. 510080 广州,中山大学附属第一医院消化内科
  • 折叠

摘要

Abstract

Randomized controlled clinical trial demonstrated that fecal microbiota transplantation (FMT)has a high efficacy in treating intestinal infection by Clostridium difficile.Although highly convincing evidence is still lacking currently,FMT has been increasingly applied in treatment of alternative diseases relat-ed to gastrointestinal dysbiosis,such as inflammatory bowel disease (IBD).The purpose of this review is to verify the origin of FMT,describe current situation of FMT,introduce practical protocol of FMT,discuss the efficacy of FMT in treatment of IBD and analyze the feasibility of FMT in treating IBD.Albeit the application of FMT still has certain problems in clinical settings,FMT is a promising option to treat IBD and deserves more attention to this field.

关键词

粪菌移植/炎症性肠病/溃疡性结肠炎/克罗恩病

Key words

Fecal microbiota transplantation/Inflammatory bowel disease/Ulcerative colitis/Crohn's disease

引用本文复制引用

廖诗乐,陈白莉,曾志荣..粪菌移植治疗炎症性肠病的现状和问题[J].新医学,2014,(9):569-572,4.

基金项目

广东省自然科学基金 ()

新医学

OACSTPCD

0253-9802

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