新医学Issue(10)：635-639,5.DOI:10.3969/g.issn.0253-9802.2014.10.001
ADAM33基因调控哮喘患儿气道重塑的机制进展
Advances in mechanisms of the regulation of ADAM33 gene on the airway remodeling in asthmatic chil-dren
李雯静 1黄花荣1
作者信息
- 1. 510120 广州，中山大学孙逸仙纪念医院儿科
- 折叠
摘要
Abstract
The pathophysiological mechanism of pediatric asthma remains elusive.Airway remodeling is part of the main pathophysiological changes which are involved in the incidence and development of asthma.A disintegrin and metalloprotease 33 (ADAM33)has been proven to be a susceptibility gene of asthma,which is closely associated with airway remodeling.This article reviewed the underlying mechanism of ADAM33 in airway remodeling in patients with asthma,and to elucidate the genetic mechanism of asthma.关键词
支气管哮喘/解整合素-金属蛋白酶33基因/气道重塑Key words
Asthma/ADAM33 gene/Airway remodeling引用本文复制引用
李雯静,黄花荣..ADAM33基因调控哮喘患儿气道重塑的机制进展[J].新医学,2014,(10):635-639,5.
