新医学Issue(10)：683-686,4.DOI:10.3969/g.issn.0253-9802.2014.10.013
低钙血液透析滤过治疗血液透析患者顽固性高血压病的疗效分析
Clinical efficacy of hemodiafiltration with low-calcium dialysate in treatment of refractory hypertension in hemodialysis patients
洪国保 1罗福漳 1黄胜 1黄桂芳 1石成钢2
作者信息
- 1. 528000 佛山，佛山市南方医科大学附属南海医院
- 2. 510630 广州，中山大学附属第三医院肾内科
- 折叠
摘要
Abstract
Objective To investigate the clinical efficacy of hemodiafiltration with low-calcium dialy-sate in treatment of refractory hypertension in hemodialysis patients.Methods Sixty-two hemodialysis patients with refractory hypertension were chosen and randomly divided into the control group,hemodiafiltration group and hemodiafiltration with low-calcium dialysate group.Based upon the basic treatment,patients in the hemo-diafiltration group received hemodiafiltration and their counterparts in the hemodiafiltration with low-calcium di-alysate group were subjected to both hemodiafiltration with 1 .25 mmol/L calcium dialysate.The course of treat-ment endured for 1 2 weeks.Results Following 1 2-week therapy,the blood pressure,β2-microglobulin,plas-ma rennin and angiotensin in the hemodiafiltration and hemodiafiltration with low-calcium dialysate groups were significantly decreased (all P <0.05),especially the more significant decrease in blood pressure of patients receiving hemodiafiltration with low-calcium dialysate (P <0.05).Conclusions Hemodiafiltration can im-prove the clinical efficacy in treatment of refractory hypertension in hemodialysis patients.Hemodiafiltration with low-calcium dialysate exert higher clinical efficacy.关键词
血液透析滤过/钙/顽固性高血压Key words
Hemodiafiltration/Calcium/Refractory hypertension引用本文复制引用
洪国保,罗福漳,黄胜,黄桂芳,石成钢..低钙血液透析滤过治疗血液透析患者顽固性高血压病的疗效分析[J].新医学,2014,(10):683-686,4.
