新医学Issue(11):710-713,4.DOI:10.3969/g.issn.0253-9802.2014.11.002
JA K/S TA T信号通路与组织器官纤维化的相关性研究进展
Research progress in correlation between the JAK/STAT signal pathway and tissue or organ fibrosis
摘要
Abstract
The JAK/STAT signal pathway is collectively mediated by a variety of cytokines and growth factors,and is extensively involved in cell proliferation,differentiation,apoptosis,immunoregulation and other pathophysiological processes. Many studies demonstrate that JAK/STAT pathway plays an important role in regulating the fibrosis process of different tissues and organs,such as kidney,liver,lung and heart.This study reviewed the correlation between the JAK/STAT signal transduction pathway and the process of tis-sue and organ fibrosis.关键词
Janus激酶/信号转导与转录激活子/信号通路/纤维化Key words
Janus kinase/Signal transducers and actirators of transcription/Signaling pathway/Fibrosis引用本文复制引用
余雄伟,陈争跃,聂振禹,包蓓艳..JA K/S TA T信号通路与组织器官纤维化的相关性研究进展[J].新医学,2014,(11):710-713,4.基金项目
浙江省自然科学基金 ()