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JA K/S TA T信号通路与组织器官纤维化的相关性研究进展

余雄伟 陈争跃 聂振禹 包蓓艳

新医学Issue(11):710-713,4.
新医学Issue(11):710-713,4.DOI:10.3969/g.issn.0253-9802.2014.11.002

JA K/S TA T信号通路与组织器官纤维化的相关性研究进展

Research progress in correlation between the JAK/STAT signal pathway and tissue or organ fibrosis

余雄伟 1陈争跃 1聂振禹 2包蓓艳2

作者信息

  • 1. 315100 宁波,宁波大学医学院
  • 2. 315100 宁波,浙江宁波市泌尿肾病医院肾内科
  • 折叠

摘要

Abstract

The JAK/STAT signal pathway is collectively mediated by a variety of cytokines and growth factors,and is extensively involved in cell proliferation,differentiation,apoptosis,immunoregulation and other pathophysiological processes. Many studies demonstrate that JAK/STAT pathway plays an important role in regulating the fibrosis process of different tissues and organs,such as kidney,liver,lung and heart.This study reviewed the correlation between the JAK/STAT signal transduction pathway and the process of tis-sue and organ fibrosis.

关键词

Janus激酶/信号转导与转录激活子/信号通路/纤维化

Key words

Janus kinase/Signal transducers and actirators of transcription/Signaling pathway/Fibrosis

引用本文复制引用

余雄伟,陈争跃,聂振禹,包蓓艳..JA K/S TA T信号通路与组织器官纤维化的相关性研究进展[J].新医学,2014,(11):710-713,4.

基金项目

浙江省自然科学基金 ()

新医学

OACSTPCD

0253-9802

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