新医学Issue(1)：20-23,4.DOI:10.3969/g.issn.0253-9802.2015.01.005
同步整合加量调强放射治疗原发性食管癌的临床疗效
Clinical efficacy of simultaneous integrated boost intensity-modulated radiation therapy for primary esophageal cancer
秦文娟 1陈龙华 2薛玉花 1徐辉3
作者信息
- 1. 510515 广州，南方医科大学南方医院放疗科
- 2. 361004厦门，厦门大学附属中山医院放疗科
- 3. 361004厦门，厦门大学附属中山医院放疗科
- 折叠
摘要
Abstract
Objective To evaluate the short-term efficacy and adverse events of simultaneous inte-grated boost intensity-modulated radiation therapy (SIB-IMRT)in the treatment of primary esophageal cancer. Methods Thirty-two patients diagnosed with primary esophageal cancer were treated with 5-or 7-field SIB-IM-RT.Gross target volume (GTV)was given at a dose of 220 cGy/F with a total dose of 6 600 cGy/30F.Clini-cal target volume (CTV)was given at a single dose of 180 cGy/F with a total dose of 5 400 cGy/30F.Results All 32 patients successfully completed the chemotherapy.The complete response rate was 81% (26 /32)and partial response rate was 13% (4 /32).The V20 of the left lung ranged from 11% to 23% and 9%-21% for the V20 of the right lung.Eleven patients (34%)presented with grade Ⅰ-Ⅱ radiation esophagitis and 6 (19%)had grade Ⅰ-Ⅱ radiation tracheitis.Conclusions SIB-IMRT is an effective therapy in treating pri-mary esophageal cancer and the adverse events are tolerable.关键词
食管癌/放射治疗/同步整合加量/调强放射治疗Key words
Esophageal cancer/Radiotherapy/Simultaneous integrated boost/Intensity-modulated radiation therapy引用本文复制引用
秦文娟,陈龙华,薛玉花,徐辉..同步整合加量调强放射治疗原发性食管癌的临床疗效[J].新医学,2015,(1):20-23,4.
