新医学Issue(1)：40-44,5.DOI:10.3969/g.issn.0253-9802.2015.01.010
5种促排卵方案对子宫腔内人工授精妊娠结局的影响
Influence of different ovarian stimulation protocols on the outcome of intrauterine insemination
叶艳娜 1陈宇栋 2贾佳 3吴泽璇 1文娅 1李予 1杨冬梓 1张清学1
作者信息
- 1. 510120 广州，中山大学孙逸仙纪念医院生殖中心
- 2. 广东省东莞卫生学校
- 3. 050000 石家庄，河北医科大学第二医院东院区妇二科
- 折叠
摘要
Abstract
Objective To compare the effects of different ovarian stimulation protocols on the clinical outcome of intrauterine insemination (IUI).Methods Clinical data of 303 infertile couples were collected during 482 IUI cycles.According to different ovarian stimulation protocols,all patients were assigned into six groups:NC (natural cycle),CC (clomiphene citrate),LE (letrozole),HMG (human menopausal gonadotro-phin),(CC +HMG)and (LE +HMG)groups.Results At HCG injection day,the endometrial of patients in HMG group were the thickest,but thinner in CC and LE group.The pregnancy rates of (CC +HMG)and (LE +HMG)groups were 26% (12 /46)and 29% (9 /31),significantly higher than those of NC (10%,16 /156)and LE groups (6%,3 /55)(all P <0.008).No statistical significance was observed among different groups in the rates of spontaneous abortion rate and multiple pregnancy(all P >0.05).Conclusion Com-bined ovarian stimulation protocols,such as CC +HMG or LE +HMG,could significantly increase the clinical pregnancy rate of IUI.关键词
子宫腔内人工授精/不同促排卵方案/临床妊娠率Key words
Intrauterine insemination/Different ovarian stimulation protocols/Clinical pregnancy rate引用本文复制引用
叶艳娜,陈宇栋,贾佳,吴泽璇,文娅,李予,杨冬梓,张清学..5种促排卵方案对子宫腔内人工授精妊娠结局的影响[J].新医学,2015,(1):40-44,5.
