新医学Issue(4)：246-249,4.DOI:10.3969/g.issn.0253-9802.2015.04.009
下肢动脉硬化性闭塞症并发急性动脉栓塞的导管接触性溶栓治疗
Application of catheter-directed thrombolysis in treatment of lower limb arteriosclerosis obliterans com-plicated with acute arterial embolism
摘要
Abstract
Objective To discuss the clinical efficacy of catheter-directed thrombolysis (CDT)in the treatment of lower limb arteriosclerosis obliterans complicated with acute arterial embolism.Methods Thirty-seven patients diagnosed with lower limb arteriosclerosis obliterans complicated with acute arterial embol-ism were treated with CDT.Prior to CDT,all patients were subjected to imaging examination to evaluate the se-verity of acute arterial embolism.Clinical efficacy of CDT was assessed by Rutherford category.Results A-mong 37 cases,21 (57%)had significant improvement,9 (24%)moderate improvement and 5 (14%)mild improvement.The efficacious rate of CDT achieved up to 81% (30 /37).Vascular injury appeared in one case during operation (had moderate improvement).Two patients (5%)presented with lower extremity gangrene including 1 case with toe gangrene (resulted in amputation).Conclusions Preoperative imaging examination plays a pivotal role in evaluating the severity of acute arterial embolism and guiding the selection of clinical therapy.CDT serves as an efficacious and relative safe treatment of lower limb arteriosclerosis obliterans com-plicated with acute arterial embolism.关键词
急性动脉栓塞/动脉硬化性闭塞症/导管接触性溶栓Key words
Acute arterial embolism/Arteriosclerosis obliterans/Catheter-directed thrombolysis引用本文复制引用
王华,陈千益,费哲为,邓超频,艾鹏..下肢动脉硬化性闭塞症并发急性动脉栓塞的导管接触性溶栓治疗[J].新医学,2015,(4):246-249,4.基金项目
温州市科技局项目 （）
