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140株嗜麦芽窄食单胞菌的临床分布及耐药性分析

尤旭 孙恒彪 黄敬 张婧 潘祖汉 陈佑明

新医学Issue(6):383-386,4.
新医学Issue(6):383-386,4.DOI:10.3969/g.issn.0253-9802.2015.06.009

140株嗜麦芽窄食单胞菌的临床分布及耐药性分析

Analysis of clinical distribution and drug resistance of 140 Stennotrophomonas maltophilia strains

尤旭 1孙恒彪 1黄敬 1张婧 1潘祖汉 1陈佑明1

作者信息

  • 1. 510630 广州,南方医科大学第三附属医院检验科
  • 折叠

摘要

Abstract

Objective To investigate the clinical distribution and drug resistance characteristics of Stenotrophomonas maltophilia (S.maltophilia)strains,aiming to provide guidelines for the clinical prevention and treatment of S.maltophilia and control of nosocomial infection.Methods A total of 1 40 S.maltophilia strains isolated from various clinical specimens from July 201 1 to June 201 4 were cultured,identified and tested for drug sensitivity by using Microscan microbial identification and subjected to antibiotic resistance analysis. The data analysis was performed by WHONET V5.5.Results Approximately 80.0% of S.maltophilia strains were detected from the respiratory tract phlegm samples,mainly distributed in intensive care unit (ICU) (35.7%),neurosurgery department (1 2.9%),and respiratory department (1 1 .4%).The overall resistance rate of 1 40 isolated strains to compound sulfamethoxazole was 7.1 %,24.3% for levfloxacin,79.3% for ce-phradine and 71 .4% for ticarcillin/clavulanate.Conclusions Most of the S.maltophilia were isolated from ICU and neurosurgery department in our hospital,dominantly from respiratory tract infection.S.maltophilia stains had relatively high sensitivity to compound sulfamethoxazole and levloxacin,and were relatively highly resistant to cephradine and ticarcillin/clavulanate.

关键词

嗜麦芽窄食单胞菌/临床分布/抗菌药物/耐药性

Key words

Stenotrophomonas maltophilia/Distribution/Antibiotics/Drug resistance

引用本文复制引用

尤旭,孙恒彪,黄敬,张婧,潘祖汉,陈佑明..140株嗜麦芽窄食单胞菌的临床分布及耐药性分析[J].新医学,2015,(6):383-386,4.

新医学

OACSTPCD

0253-9802

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