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隐匿性乙型肝炎病毒感染的机制及其对血液安全的影响

张蕾琳 张轩

临床医学工程Issue(5):670-672,3.
临床医学工程Issue(5):670-672,3.DOI:10.3969/j.issn.1674-4659.2014.05.0670

隐匿性乙型肝炎病毒感染的机制及其对血液安全的影响

Mechanism of Occult Hepatitis B Virus Infection and Its Effect on Blood Safety

张蕾琳 1张轩2

作者信息

  • 1. 广州血液中心,广东广州510095
  • 2. 广东省中医院,广东广州510006
  • 折叠

摘要

Abstract

HBV DNA can be detected in one's serum or liver who is HBsAg negative in serum, and this phenomenon is called occult hepatitis B virus infection (OBI). OBI makes it particularly difficult to ensure blood transfusion safety, make clinical diagnosis and imple-ment epidemiological monitoring of HBV. Further study for the mechanism is beneficial for its prevention and treatment. This paper re-viewed the research progress of the mechanism of OBI in recent years, the impact on blood safety, and the promoting effect on blood safety of nucleic acid test.

关键词

隐匿性乙肝病毒感染/基因突变/核酸检测/血液安全

Key words

Occult hepatitis B virus infection/Gene mutation/Nucleic acid detection/Blood safety

分类

医药卫生

引用本文复制引用

张蕾琳,张轩..隐匿性乙型肝炎病毒感染的机制及其对血液安全的影响[J].临床医学工程,2014,(5):670-672,3.

临床医学工程

1674-4659

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