临床医学工程Issue(7)：809-811,3.DOI:10.3969/j.issn.1674-4659.2014.07.0809
重复经颅磁刺激对抑郁症的疗效及主观睡眠质量的影响
Therapeutic Effect of Repetitive Transcranialmagnetic Stimulation (rTMS) and Its Influence on Subjective Sleep Quality on Patients with Depression
摘要
Abstract
Objective To understand the therapeutic effect of the repetitive transcranial magnetic stimulation (rTMS) and its influence on subjective sleep quality on patients with depression. Methods 60 eligible depression patients were randomly divided into research group (treated with rTMS and citalopram) and control group (treated with citalopram only). The treatment lasted for four weeks. The clinical effect was evaluated by the Hamilton Depression Scale (HAMD-17) and the Pittsburgh Sleep Quality Index (PSQI) before and after treatment. At the end of the study, we also evaluated the Treatment Emergent Symptom Scale (TESS). Results ①The therapeutic effect to depression of the two groups were similar, without statistical difference between the two groups.②At the end of the study, the scores of PSQI of the two groups were lower than before, with significant difference in contrast to pre-therapy;At the same time, the score of PSQI of the research group was lower than that of the control group, with statistical difference between the two groups.③The TESS scores concerning severity of side effects and pain had no statistical difference between the two groups. Conclusions The therapy of rTMS combined with antide-pressant drugs is effective to depression and the patients' subjective sleep quality, which is feasible to apply in clinic.关键词
重复经颅磁刺激/抑郁症/主观睡眠质量/匹兹堡睡眠质量指数Key words
Repetitive transcranial magnetic stimulation/Depression/Subjective sleep quality/Pittsburgh sleep quality index分类
医药卫生引用本文复制引用
邓娟,刘联琦,侯彩兰,周平..重复经颅磁刺激对抑郁症的疗效及主观睡眠质量的影响[J].临床医学工程,2014,(7):809-811,3.基金项目
广东省自然科学基金项目 （）
