临床医学工程Issue(10)：1252-1254,3.DOI:10.3969/j.issn.1674-4659.2014.10.1252
芬太尼静脉术后镇痛对糖尿病患者胰岛功能的影响
Effect of Fentanyl on the Function of Pancreas Islet of Diabetic Patients During Postoperative Analgesia
摘要
Abstract
Objective To investigate the effect of fentanyl serving as postoperative analgesia drugs on the diabetic patients' islets. Methods 50 cases ofⅠdiabetic patients conformed to the WHO diagnostic criteria were selected and randomly divided into groupⅠ(25 cases) and groupII(25 cases). The groupⅠreceived nothing, while the gorupIIused fentanyl as postoperative analgesia drugs, the dispensing of the analgesia pump were fentanyl (1.5 mg)+azasetron (10 mg)+NaCl (0.9%), then conpounded it to 100 mL, the flow was 2 mL/h, and the first intravenous injection of fentanyl was 50 μg. Patirnts without diabetes were also selected as control group (25 cases). The blood glucose and insulin of three group were detected 30 min preoperatively, and 12 h, 24 h, 48 h, 72 h postoperatively. Results The patients' blood glucose concentration at the time of 12 h, 24 h, 48 h postoperative in groupIIwas significantly lower than those of groupⅠ(P<0.05), but the insulin concentration had no difference between the two groups (P >0.05). Conclusions The application of fentanyl using in postoperative analgesia can better control the blood glucose of the diabetic patients and has no effects on the secretion of insulin.关键词
芬太尼/糖尿病/胰岛/术后镇痛Key words
Fentanyl/Diabetes/Islet/Postoperative analgesia分类
医药卫生引用本文复制引用
钱滔来,杨鹍华,高玲..芬太尼静脉术后镇痛对糖尿病患者胰岛功能的影响[J].临床医学工程,2014,(10):1252-1254,3.基金项目
深圳市医学科研项目 （）
