摘要
Abstract
Objective To evaluate cardiac structural and functional changes of fetuses whose mothers have gestationed diabetes. Methods 60 cases of pregnant women (diagnosed as gestational diabetes mellitus) delivered in our hospital from January to December 2012 were selected as the experimental group, and 60 cases of normal pregnant women with gestational age in the same period were selected as the control group. Patients in both of the two groups were given fetal echocardiography in late pregnancy to measure left/right ventricular systolic diameters (LVDs, RVDs), left/right ventricular diastolic diameter(LVDd, RVDd), left/right ventricular wall thickness (IVWT, RVWT), and inter-ventricular septum shrink/diastolic thickness (IVSs, IVSd);meanwhile left ventricular ejection fraction (LVEF), mitral and tricuspid E, A peak velocity ratio (E/AMV, E/ATV), and ventricular Tei indexes were calculated. And all measures were compared between the two groups. Results There were no signiifcant differences between the two groups on LVDs, RVDs, LVDd, RVDd (P>0.05) while the values of LVWT, RVWT, IVSs, IVSd of the diabetes group were higher than those of the control group with signiifcant differences (P<0.05). There was no signiifcant difference between the two grou1ps on LVEF values while the left and right cardiac output values of the diabetes group were signiifcantly higher than those of the control group (P<0.05), E/ATV values of the diabetes group were lower than those of the control group (P<0.05);the left and right ventricular Tei index values of the diabetes group were signiifcantly higher than those of the control group (P<0.05). Conclusion The cardiac structures and functions of fetus of pregnant women with gestational diabetes are significantly changed compared with normal fetuses. Echocardiography can effectively monitor the fetal cardiac functions, and provide the basis for early intervention and treatment of pregnancy.关键词
妊娠期糖尿病/胎儿/心脏功能/超声心动图Key words
gestational diabetes/fetus/cardiac function/echocardiogram分类
医药卫生
