摘要
Abstract
Objective To explore the application value of Dual-source CT volume perfusion imaging in the diagnosis of solitary pulmonary nodules (SPNs). Methods 116 cases of SPNs confirmed by pathological diagnosis in our hospital from March 2011 to December 2013 were chosen. All the patients were examined by Dual-source CT perfusion scans, and then we observed the characteristics of CT imaging and analyzed the blood volume (BV), blood lfow (BF), permeability surface (PS), mean transit time (MTT) to calculate average perfusion values of SPNs’ measurable layer. Benign and malignant groups were divided according to the results of pathological diagnosis. Results The values of BV, BF and PS in malignant group were (4.63±1.52) mL/100g, (98.36±48.25) mL/(100g•min) and (17.23±7.65) mL/(100g•min) respectively, and these values were obviously higher than those of benign group, whose values were (2.28±1.76) mL/100g, (46.33±30.23) mL/(100g•min) and (7.42±7.28) mL/(100g•min), respectively. There were signiifcant differences in BV, BF and PS values between malignant group and benign group (P<0.05). The values of MTT in benign group and malignant group were (5.13±2.52) s and (6.16±4.88) s, respectively, and the differences in MTT values between two groups were not signiifcant (P>0.05). In diagnosing benign and malignant SPNs, the diagnosis sensitivities based solely on BV, BF or PS were 95%, 91%and 86%, respectively and the specificities were 68%, 64%and 77%, respectively. The diagnosis sensitivities of BV+PS and BF+PS were both 82%, which is higher than that of using a single indicator. Conclusion The application of Dual-source CT volume perfusion technology can improve the detection rate of SPNs and provide evidences for early conifrmation of SPN.关键词
双源CT容积灌注成像技术/孤立性肺结节/血容量/血流量/表面通透性Key words
dual-source CT volume perfusion imaging technology/solitary pulmonary nodule/blood volume/blood lfow/permeability surface分类
医药卫生
