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阿尔茨海默病患者弥散张量成像研究

李辉 陶磊 倪萍 聂玫 吴清清 吴玉珍 陈自谦

中国医疗设备Issue(11):1-4,4.
中国医疗设备Issue(11):1-4,4.DOI:10.3969/j.issn.1674-1633.2014.11.001

阿尔茨海默病患者弥散张量成像研究

Study on Diffusion Tensor Imaging of Alzheimer's Patients

李辉 1陶磊 1倪萍 2聂玫 1吴清清 1吴玉珍 1陈自谦1

作者信息

  • 1. 南京军区福州总医院 医学影像科,福建 福州 350025
  • 2. 南京军区福州总医院 医学工程科,福建 福州 350025
  • 折叠

摘要

Abstract

Objective To explore the changes of FA values obtained by diffusion tensor imaging (DTI) study of patients suffered from Alzheimer’s disease.Methods 17 cases of AD and 17 cases of controls underwent DTI scan using Siemens Magnetom TrioTim 3.0T MR scanner. Fractional anisotropy (FA) values of ROI in white matter tracts and DMN regions were obtained, and FA values of the two groups were compared. Results FA values in different zones in DMN and various regions of interest which represent different types of fibers were lower in AD patients than that in the control group.Conclusion There were typical changes of DTI in AD patients, and it may help the early diagnosis of the disease.

关键词

超导磁共振机/阿尔茨海默病/弥散张量成像/默认模式网络

Key words

superconducting MRI/Alzheimer's disease/diffusion tensor imaging/default mode network

分类

医药卫生

引用本文复制引用

李辉,陶磊,倪萍,聂玫,吴清清,吴玉珍,陈自谦..阿尔茨海默病患者弥散张量成像研究[J].中国医疗设备,2014,(11):1-4,4.

基金项目

福建省社会发展科技重点项目(2012Y0057);南京军区重大课题(10Z030)。 ()

中国医疗设备

OACSTPCD

1674-1633

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