摘要
Abstract
Objective To study the effectiveness of application of low radiation dose and low-iodine-content contrast agent in coronary CTA (Computed Tomography Angiography). Methods Altogether 90 volunteers were selected from the patients who had hypothesized as suspected coronary diseases from January 2014 to July 2014 in the hospital. Having been randomly and evenly divided into 3 groups, all the patients underwent coronary CTA. The conventional tube voltage (120 kV) and 70 mL iohexol contrast agent (350 mgI/mL) were adopted in Group A. The low tube voltage (100 kV) and 70 mL iohexol contrast agent (300 mgI/mL) were used in Group B. As for Group C, the low tube voltage (100 kV) and 50mL iohexol contrast agent (300 mgI/mL) were used. After segmental analysis of the coronary artery through post-process of CTA images, comparisons were made among three groups in the aspects of image quality and diagnostic results. Results There were no statistically significant differences among three groups in the evaluation scores of their image quality (P>0.05). The segment evaluation rate of three groups were 97.40%, 96.61% and 96.36% respectively without statistically significant differences (χ2=0.73, P>0.05). The excellent rate of segments in three groups were 93.23%, 92.69% and 92.47% respectively without statistically significant differences (χ2=0.18, P>0.05). The radiation dose of the three group were (3.87±0.58), (2.89±0.54) and (2.33±0.48) mSv with statistically significant differences (P<0.05). And the iodine content of the three groups were 24.5, 21.0 and 15.0g with statistically significant differences (P<0.05). Conclusion When the low radiation dose and low-iodine-content contrast agent were used in CTA, it was recommended to obviously reduce the radiation dose and iodine content while the image quality could meet the requirements of clinical diagnosis. This methodology was of great significance in clinical applications.关键词
低辐射剂量/低管电压/低碘含量/冠状动脉CT血管成像/螺旋CT机Key words
low radiation dose/low tube voltage/low iodine content/coronary computed tomography angiography/spiral CT分类
医药卫生
