中国医疗设备Issue(6)：33-38,6,7.DOI:10.3969/j.issn.1674-1633.2015.06.007
T1 mapping定量技术评价左室不同区域心肌初始T1值的初步研究
A Preliminary Study of the Quantitative T1 Mapping Technique in Evaluation of the Native Left Ventricular Myocardial T1 Value in Different Segments
刘明熙 1祝红线 1刘洁 1张挽时 1张子衡 2周振宇 1解立志 1孟利民 1徐先荣 1田建伟 1龚万沣1
作者信息
- 1. 空军总医院 CT MR科室，北京100142
- 2. GE医疗北京磁共振研究中心，北京 100176
- 折叠
摘要
Abstract
Objectives To investigate the clinical feasibility and repeatability of a MLLSR [Modified Look-Locker FIESTA (Fast Imaging Employing Steady State Acquisition) Imaging with Saturation Recovery]-based quantitative T1 mapping technique in 3.0T CMR (Cardiac Magnetic Resonance) to evaluate the left ventricular myocardial T1native values in different segments.Methods Altogether 30 healthy volunteers were selected and scanned by CMR on the sequence of Cine imaging, T2WI and T1 mapping so as to perform quantitative measurement of ROI (Region of Interest) T1native values. Then, the independent-samplesT test and ANOVA (Analysis of Variance) were deployed to analyze the difference of the T1native values in 17 segments of myocardium, different coronary arterial blood supply areas, age and gender.Results There were differences of the T1native values between some segmental myocardia(P<0.01). The mean myocardial T1native and T1native of blood pool were:(717.6±100.6) ms and (1208.9±224.2) ms at the base; (773.9±101.2) ms and (1281.2±251.7) ms in the middle; (955.4±191.1) ms and (1829.6±584.8) ms at the apex, respectively. Apical T1native values of myocardium and blood pool were higher than the basal and the middle (P<0.01). Also, statistically significant differences (F=47.862,P<0.01) existed in T1native values of different coronary arterial blood supply areas.Conclusion The CMR MLLSR T1 mapping technique had demonstrated its excellent feasibility and repeatability, which revealed segmented variations in evaluation of left ventricular myocardial T1native values.关键词
心脏磁共振/T1 mapping/改进的Look-Locker稳态自由进动饱和恢复/健康志愿者Key words
cardiac magnetic resonance/T1 mapping/modified Look-Locker FIESTA imaging with saturation recovery/healthy volunteers分类
信息技术与安全科学引用本文复制引用
刘明熙,祝红线,刘洁,张挽时,张子衡,周振宇,解立志,孟利民,徐先荣,田建伟,龚万沣..T1 mapping定量技术评价左室不同区域心肌初始T1值的初步研究[J].中国医疗设备,2015,(6):33-38,6,7.
