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碳酸镧治疗维持性透析患者并发高磷血症疗效观察

陈晓霞 卢媛 楼季庄

疑难病杂志Issue(6):604-607,4.
疑难病杂志Issue(6):604-607,4.DOI:10.3969/j.issn.1671-6450.2014.06.018

碳酸镧治疗维持性透析患者并发高磷血症疗效观察

Lanthanum carbonate treatment of maintenance hemodialysis patients with hyperphosphatemia

陈晓霞 1卢媛 1楼季庄1

作者信息

  • 1. 210029 南京医科大学附属南京医院/南京市第一医院血液净化中心
  • 折叠

摘要

Abstract

Objective To evaluate the effectivenes of lanthanum carbonate for hyperphosphatemia in patients under -going maintenance hemodialysis .Methods According to whether taking lanthanum carbonate or not , patients were divided into observation group and control group .Lanthanum carbonate observation group of 16 cases, were treated with lanthanum carbonate, every time 500 mg, 2-3 times/d;23 cases in the control group , oral calcium carbonate .0.75 g,twice aday.Re-sults Compared with before treatment , treatment for 1, 2, 6 months later, the observation group serum phosphorus levels were decreased ( P <0.01), the control group decreased not obviously ( P >0.05), and the observation group serum phos-phorus decreased significantly [(1.80 ±0.25 )mmol/L vs.(2.21 ±0.33) mmol/L, (1.56 ±0.19) mmol/L vs.(2.28 ± 0.26) mmol/L, (1.51 ±0.17) mmol/L vs.(2.29 ±0.25) mmol/L]( P <0.01) than those in the control group.The 2 groups of calcium decreased not significantly ( P >0.05);after 6 months of treatment, compared with the control group, the observation group PPTH decreased more significantly [(614.80 ±178.38) pg/ml vs.(982.63 ±716.34) pg/ml] ( P <0.05).Conclusion Lanthanum carbonate treatment of maintenance hemodialysis patients with hyperphosphatemia is better than the traditional method is effective in the treatment of phosphorus reduction .

关键词

高磷血症/碳酸镧/透析,维持性

Key words

Hyperphosphatemia/Lanthanum carbonate/Hemodialysis ,maintenance

引用本文复制引用

陈晓霞,卢媛,楼季庄..碳酸镧治疗维持性透析患者并发高磷血症疗效观察[J].疑难病杂志,2014,(6):604-607,4.

疑难病杂志

OACSTPCD

1671-6450

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