摘要
Abstract
Objective To evaluate the effectivenes of lanthanum carbonate for hyperphosphatemia in patients under -going maintenance hemodialysis .Methods According to whether taking lanthanum carbonate or not , patients were divided into observation group and control group .Lanthanum carbonate observation group of 16 cases, were treated with lanthanum carbonate, every time 500 mg, 2-3 times/d;23 cases in the control group , oral calcium carbonate .0.75 g,twice aday.Re-sults Compared with before treatment , treatment for 1, 2, 6 months later, the observation group serum phosphorus levels were decreased ( P <0.01), the control group decreased not obviously ( P >0.05), and the observation group serum phos-phorus decreased significantly [(1.80 ±0.25 )mmol/L vs.(2.21 ±0.33) mmol/L, (1.56 ±0.19) mmol/L vs.(2.28 ± 0.26) mmol/L, (1.51 ±0.17) mmol/L vs.(2.29 ±0.25) mmol/L]( P <0.01) than those in the control group.The 2 groups of calcium decreased not significantly ( P >0.05);after 6 months of treatment, compared with the control group, the observation group PPTH decreased more significantly [(614.80 ±178.38) pg/ml vs.(982.63 ±716.34) pg/ml] ( P <0.05).Conclusion Lanthanum carbonate treatment of maintenance hemodialysis patients with hyperphosphatemia is better than the traditional method is effective in the treatment of phosphorus reduction .关键词
高磷血症/碳酸镧/透析,维持性Key words
Hyperphosphatemia/Lanthanum carbonate/Hemodialysis ,maintenance