疑难病杂志Issue(6)：615-618,4.DOI:10.3969/j.issn.1671-6450.2014.06.022
自拟柴郁寄生汤治疗肝郁肾虚型高泌乳素血症月经后期临床研究
Research on the clinical effect of Chaiyujisheng decoction in dealing with hyperprolactinemia with late menstruation
摘要
Abstract
Objective To observe the effect of Chaiyujisheng decoction week therapy with soothing the liver and in-vigorating the kidney in the treatment of liver and kidney deficiency type hyperprolactinemia menstruation , and to explore its mechanism of action .Methods 60 cases of hyperprolactinemia late menstruation patients , randomly divided into treatment group (Chaiyujisheng decoction) and control group (bromocriptine) with 30 cases in each group.To observe the clinical cur-ative effect before and after treatment , TCM symptoms, blood prolactin ( PRL) and the association between hormone ( E2 , LH) , and compare the effects of the two therapy .Results Compared with before treatment , index scores of the 2 groups after treatment were improved, the difference was statistically significant ( P <0.05);treatment group in improving the menstrual cycle and symptom , breast distending pain , menstrual distending pain in the lower abdomen and other symptoms are signifi -cantly better than the control group ( P <0.05), the treatment group the total symptom score index was 81.0%, control group 33.0%.Compared with before treatment, the 2 groups after treatment PRL, P, LH, E2 levels decreased ( P <0.05), and the treatment group E2 levels significantly better than the control group ( P <0.05), there were no significant differences in FSH levels in the 2 groups before and after treatment ( P >0 .05 ) .The 2 group total effectiveness have statistics signifi-cance (86.7%vs.73.3%, P <0.05).Conclusion It demonstrated that the Chaiyujisheng decoction week therapy with soothing the liver and invigorating the kidney in treatment of hyperprolactinemia is safe , effective .关键词
高泌乳素血症/月经后期/肝郁肾虚Key words
Hyperprolactinemia/Late menstruation/Liver depression and kidney deficiency引用本文复制引用
张芸娜,金哲,睢丛璐,佟庆,徐翠,徐彩,林彤..自拟柴郁寄生汤治疗肝郁肾虚型高泌乳素血症月经后期临床研究[J].疑难病杂志,2014,(6):615-618,4.基金项目
北京中医药大学自主选题资助项目 （）
