摘要
Abstract
Objective To investigate the clinical efficacy of edaravone combined with Xingnaojing injection in the treatment of senile acute cerebral hemorrhage and its effect on inflammatory factors .Methods According to standard diagnosis of cerebral hemorrhage , 98 cases of elderly patients were randomly divided into observation group and control group with 49 ca-ses in each group , the control group on the basis of conventional therapy , given edaravone , the observation group were given edaravone, Xingnaojing injection treatment.The 2 groups were treated for 14 d, neurologic function deficit score (NIHSS), the Montreal cognitive assessment (MoCA), activities of daily living (ADL) score of the 2 groups were assessed, the detec-tion of levels of inflammatory factors of TNF-alpha, IL-1, IL-6 were recorded, and observed the clinical curative effect .Re-sults Compared with those of before treatment , after treatment 2 groups'NIHSS, MoCA and ADL score were significantly im-proved ( P <0.05), the observation group was significantly better than the control group ( P <0.05);compared with before treatment, after treatment 2 groups'plasma levels of inflammatory factor were significantly reduced ( P <0.05), and the ob-servation group 7 daus.14 days after treatment were significantly lower than the control group ( P <0.05).In observation group , the cure rate was 53.1%, the total efficiency was95.9%, significantly higher than those of control group of 28.6%and 75.5%, the difference was statistically significant ( P <0.05).Conclusion Edaravone combined with Xingnaojing in-jection in the treatment of elderly patients with acute intra-cerebral hemorrhage , and it is worth for clinical promotion .关键词
脑出血,急性/依达拉奉/醒脑静注射液/炎性因子Key words
Cerebral hemorrhage , acute/Edaravone/Xingnaojing injection/Inflammatory factor
