疑难病杂志Issue(7)：714-716,720,4.DOI:10.3969/j.issn.1671-6450.2014.07.017
国内成人肝母细胞瘤37例临床特点分析
Analysis on the domestic clinical characteristics of 37 cases with adult hepatoblastoma
摘要
Abstract
Objective To investigate the clinical features of domestic adult hepatoblastoma (hepatoblastoma, HB) and provide a reference for clinical diagnosis and treatment .Methods Retrieval search biomedical Chinese literatures of the database, the deadline was December 31, 2013, searched all the published adult HB literature , collected and analyzed the lit-erature with clinical pathological demonstrated cases , analysis items including gender , age, the main clinical manifestations , laboratory examination, imaging examination, treatment and prognosis.Results There were 24 papers, 37 cases of adult HB were enrolled.Men and women about 1.64∶1 (23/14), relatively more commonly found in the age of 40~60 years (18/37, 48.65%).Abdominal pain (54.05%, 20/37), abdominal distension (48.65%, 18/37) and abdominal mass (22.22%, 8/37) are the most common clinical manifestations , but lack of specificity.About half of the cases (48.39%, 15/31) with elevated plasma AFP , AFP levels after treatment were decreased .Risk factor for hepatitis B is not adult HB .Ultrasound and CT examination are the most commonly used image methods in the diagnosis of adult HB , but lack of specificity .Tumors are more commonly found in the right lobe of the liver (54.05%, 20/37), about half of the patients had different degree of infil-tration and metastasis at diagnosis .Adult HB misdiagnosis rate is high , is easy to be misdiagnosed as hepatocellular carcino-ma.Operation is the most commonly used method of treatment , chemotherapy is an important therapeutic tool .Adult HB's prognosis slightly better than liver cancer , the median survival time was 6 months.Conclusion Adult HB studies show a lack of specificity of the clinical and imaging character , in clinical work should be alert to the presence of adult HB .Operation is the first choice of treatment of adult HB , chemotherapy is an important therapeutic tool .关键词
成人/肝母细胞瘤/临床特点Key words
Adult/Hepatoblastoma/Clinical characteristics引用本文复制引用
李哲,李光兵,刘军..国内成人肝母细胞瘤37例临床特点分析[J].疑难病杂志,2014,(7):714-716,720,4.基金项目
国家自然基金面上项目 （）
